'''Question:''' What about the support for icosahedral viruses? '''Answer:''' EMAN supports icosahedral symmetry similarly to other symmetries. Basically you will follow the same procedures as for particles of other symmetries. Of course, you need to specify '''sym=icos''' for the '''refine''' command. To build initial model, you can use '''starticos''' program. If you still have questions specific to icosahedral viruses, please contact Dr. Wen Jiang who made most of the changes in EMAN to support icosahedral symmetry well.